As the world moves forward, so must the approach to rethinking aesthetic treatments. The need is not for evolution, but revolution. Novoxel® stands for new thinking and excellence in innovation. We have created a breakthrough technology that harnesses the power of nature for a unique treatment solution that’s greener and cleaner: TMA®. Through combining heat and motion, skin is regenerated and healed – safely, non-invasively, effectively. All the incredible benefits of TMA® have been incorporated into our flagship aesthetic platform: Tixel®. Compact and easy to use, Tixel® is simplicity itself yet can address a whole range of patient and physician needs. This is just one of the ways in which we seek to go forward in motion. And go beyond. The newest member of the Tixel family of products, Tixel i®, was cleared by FDA for application of localized heat and pressure for patients with Evaporative Dry Eye due to Meibomian Gland Dysfunction (MGD).
Treat multiple body areas, including face, neck and décolleté, with very short downtime and high patient satisfaction. This non-invasive, lunch-time treatment provides noticeable results within just a few short sessions.
Natural heat is applied to the skin by a medical-grade titanium tip in situ that is not only self-sterilizing but also reusable and easy to clean. There is no emitted radiation, smoke, fumes or bleeding.
Tixel® is simple to operate, with a quick learning curve. Its handpiece is light and there are no disposables.
Tixel® creates a whole new dimension in ergonomic design. Compact and light, it not only enables users to save space but also to benefit from significant savings in equipment, operation, and maintenance.
Natural heat is applied to the skin by a medical-grade titanium tip in situ that is not only self-sterilizing but also reusable and easy to clean. There is no emitted radiation, smoke, fumes or bleeding.
Tixel® creates a whole new dimension in ergonomic design. Compact and light, it not only enables users to save space but also to benefit from significant savings in equipment, operation, and maintenance.
Treat multiple body areas, including face, neck and décolleté, with very short downtime and high patient satisfaction. This non-invasive, lunch-time treatment provides noticeable results within just a few short sessions.
Tixel® is simple to operate, with a quick learning curve. Its handpiece is light and there are no disposables.
Tixel® is powered by our proprietary TMA® technology. It is the only fractional skin resurfacing device to transfer thermal energy directly to skin – by conduction, the most effective form of heat transfer. Heat is applied to skin by a medical-grade in situ self-sterilizing titanium tip, triggering the natural healing and skin rejuvenation processes.
Fractional vaporization of tissue with an oscillatory array of high temperature rods: part I: ex vivo study
Gary Lask , Monica Elman, Nathalie Fournier, Michael SlatkineFractional treatment of aging skin with Tixel, a clinical and histological evaluation
Monica Elman, Nathalie Fournier, Gilbert Barnéon, Eric F. Bernstein, Gary LaskA novel thermo-mechanical system enhanced transdermal delivery of hydrophilic active agents by fractional ablation
Amnon C. Sintov, Maja A. HofmannThe toxic edge-A novel treatment for refractory erythema and flushing of rosacea
Or Friedman, Amir Koren, Roni Niv, Joseph N. Mehrabi, Ofir ArtziTreatment of port wine stain with Tixel-induced rapamycin delivery following pulsed dye laser application
Ofir Artzi, Jos N. Mehrabi, Lee Heyman, Or Friedman, Jacob MashiahThe Scar Bane, Without the Pain: A New Approach in the Treatment of Elevated Scars: Thermomechanical Delivery of Topical Triamcinolone Acetonide and 5-Fluorouracil
Ofir Artzi, Amir Koren, Roni Niv, Joseph N. Mehrabi, Or FriedmanA new approach in the treatment of pediatric hypertrophic burn scars: Tixel-associated topical triamcinolone acetonide and 5-fluorouracil delivery
Ofir Artzi, Amir Koren, Roni Niv, Joseph N Mehrabi, Jacob Mashiah, Or FriedmanA New Method for Percutaneous Drug Delivery by Thermo-Mechanical Fractional Injury
Ronen Shavit, Christine DierickxAn enhanced transcutaneous delivery of botulinum toxin for the treatment of Hailey-Hailey disease
Efrat Bar-Ilan, Amir Koren, Wasim Shehadeh, Jacob Mashiah, Eli Sprecher, Ofir ArtziThermomechanical Ablation-Assisted Photodynamic Therapy for the Treatment of Acne Vulgaris. A Retrospective Chart Review of 30 Patients
Y Hilerowicz, O Friedman, E Zur, R Ziv, A Koren, F Salameh, J N Mehrabi, O ArtziEnhanced percutaneous delivery of Beta-blockers using thermal resurfacing drug delivery system for topical treatment of infantile hemangiomas.
Jacob Mashiah, Efrat Bar-Ilan, Amir Koren, Or Friedman, Eyal Zur, Ofir ArtziWound Healing Process After Thermomechanical Skin Ablation
G Kokolakis, L von Grawert, M Ulrich, J Lademann, T Zuberbier, M HofmannThermo‐Mechanical Fractional Injury Enhances Skin Surface‐ and Epidermis‐ Protoporphyrin IX Fluorescence: Comparison of 5‐Aminolevulinic Acid in Cream and Gel Vehicles
C Foged, M Haedersdal, L Bik, C Dierickx, P A Phillipsen, K Togsverd-BoThermo‐Mechanical Fractional Injury Therapy for Facial Skin Rejuvenation in Skin Types II to V: A Retrospective Double‐Center Chart Review
Danny Daniely, Harryono Judodihardjo, Sajjad F Rajpar, Joseph N Mehrabi, Ofir ArtziTreatment of periorbital wrinkles using thermo‐mechanical fractional injury therapy versus fractional non‐ablative 1565 nm laser: A comparative prospective, randomized, double‐arm, controlled study
Fares Salameh, Danny Daniely, Arielle Kauvar, Rafael L Carasso, Joseph N Mehrabi, Ofir ArtziRetrospective study on the safety and tolerability of clinical treatments with a novel Thermomechanical Ablation device on 150 patients
Harryono Judodihardjo, Sajjad RajparEfficacy and safety of thermomechanical fractional injury‐assisted corticosteroid delivery versus intralesional corticosteroid injection for the treatment of hypertrophic scars: A randomized split‐scar trial
W Manuskiatti, C Yan, O Artzi, M K R Gervasio, R WanitphakdeedechaEfficacy and safety of a thermal fractional skin rejuvenation system (Tixel) for the treatment of facial and/or scalp actinic keratoses
Shabtai, Sloutsky, Lapidoth, Mimouni, Chorny, Snast, Leshem, Friedland, Hodak, Klein, Agmon, LeviEvaluation of Device-Based Cutaneous Channels Using Optical Coherence Tomography: Impact for Topical Drug Delivery
Jordan V Wang, Joseph N Mehrabi, Christopher B Zachary, Roy G GeronemusThe effect of thermo-mechanical device (Tixel) treatment on evaporative dry eye disease - A pilot prospective clinical trial
M Safir, I Hecht, A Ahimor, S Zmujack-Yehiam, R Stein, E Bakshi, A Einan-Lifshitz 2, M E HartsteinThe effect of non-ablative thermomechanical skin treatment (Tixel®) on dry eye disease: A prospective two centre open-label trial
Sunil Shah, Debarun Dutta, Ankur Barua, Ludger Hanneken, Shehzad A NarooImpact of thermo-mechanical skin treatment on refraction and keratometry in patients with dry eye disease and the implications for cataract surgery
Marta Blanco-Vázquez, Raquel Gil-Cazorla, Ankur Barua, Mukesh Taneja, Ludger Hanneken, Sunil ShahComprehensive Review of Thermomechanical Fractional Injury Device: Applications in Medical and Cosmetic Dermatology
Blanca Estupiñan, Adam Souchik, Alexandra Kiszluk, Shraddha DesaiProspective Evaluation of the Safety and Efficacy of Thermomechanical Fractional Injury for Perioral Rhytides
Jordan V Wang, Shirin Bajaj, Alexa Steuer, David Orbuch, Roy G GeronemusSafety and Efficacy of a Thermomechanical Fractional Injury Device for Periorbital Rhytides
Jordan V Wang, Shirin Bajaj, David Orbuch, Moshe Lapidoth, Ifat Klein, Yael Agmon GersteEffectiveness and safety of a thermo-mechanical action device versus thermal pulsation device in the treatment of meibomian gland dysfunction
E Sadri, A Verachtert, G D Parkhurst, J Echegoyen, I Klein, Y G Agmon, G J BerdyFrontal Fibrosing Alopecia-Related Facial Papules Successfully Treated With a Thermomechanical Fractional Injury Device
Taciana Dal'Forno, Martina Souilljee BirckThermomechanical Fractional Injury Therapy Delivers Satisfactory Results, Less Pain With Surface Anesthesia
Richard Mark KirknerPercutaneous delivery of liquid tetracycline using a thermal resurfacing drug delivery system for the treatment of festoons
Margarita Safir, Inbar Waizer, Ari Safir, Morris E Hartstein, Ofir ArtziSafety and Effectiveness of a Thermo-Mechanical Fractional System at Low Settings for the Treatment of Photodamage
Eric F Bernstein, Maggie Wang, Jennifer Wang, J Lee Pannell