TMA® is a technology, specially developed by Novoxel®, that’s forward in thinking and in its action. It uniquely combines motion and heat with the forward movement of a medical-grade titanium tip. This proprietary non-laser fractional technology transfers thermal energy to skin very quickly and safely: energy is emitted through a matrix of tiny pyramid-shaped pins made of biocompatible materials covering a treatment area of 1cm². The pins are heated to a temperature of 400°C and are self-sterilized.
During treatment, the pins are introduced to the surface of the skin at a precisely-controlled speed and create brief contact with the skin lasting only a few milliseconds. This enables the thermal energy stored in the pins to be transferred to the skin. The thermal transfer results in an array of tiny non-ablative coagulation sites. Because the tiny tip pyramids hold a limited amount of energy, burns and tissue charring are prevented.
The reason why pain is relatively low during treatment with Tixel® compared to the ablative CO₂ laser is primarily due to the transfer of a relatively lower amount of energy to the skin by Tixel®. This is made possible by utilization of a more efficient energy transfer method (conduction vs. radiation) and the longer pulse duration (e.g. 10ms vs. 1ms) of Tixel as compared to the CO₂ laser.
Research shows that TMA™ creates superficial channels in the stratum corneum, allowing enhanced permeability to topically applied hydrophilic substances, that are applied after treatment. Tixel®’s intended use does not currently include tissue permeability enhancement.
The effect of thermo-mechanical device (Tixel) treatment on evaporativ..Sunil Shah a,b, Debarun Dutta a, Ankur Barua b, Ludger Hanneken c, Shehzad A. Naroo a,
The effect of thermo-mechanical device (Tixel) treatment on evaporativ..Margarita Safir *, Idan Hecht, Alon Ahimor, Sigal Zmujack-Yehiam, Ran Stein, Erez Bakshi, Adi Einan-
Efficacy and safety of a thermal fractional skin rejuvenation syste..Nadezhda Sloutsky, Moshe Lapidoth, Daniel Mimouni, Ilia Chorny, Igor Snast, Yael Anne Leshem, Rivka
Efficacy and safety of thermomechanical fractional injury‐assisted c..Woraphong Manuskiatti MD, Chadakan Yan MD, Ofir Artzi MD, Mia Katrina R. Gervasio, Rungsima Wanitph
Retrospective study on the safety and tolerability of clinical treatme..Harryono Judodihardjo, MB BCh BAO (Belfast), MSc (Cardiff), PhD (Cardiff), DipGUM (London), Sajjad R
Thermo‐Mechanical Fractional Injury Enhances Skin Surface‐ and Epi..Camilla Foged, Merete Haedersdal, Liora Bik, Christine Dierickx, Peter Phillipsen, Katrine Togsverd
Thermo‐Mechanical Fractional Injury Therapy for Facial Skin Rejuvena..Danny Daniely, MD, Harryono Judodihardjo, MB, BCh, BAO, MSC, PhD, Sajjad F. Rajpar, MB, ChB, FRCP,
A New Method for Percutaneous Drug Delivery by Thermo-Mechanical Fract..Ronen Shavit, MSc and Christine Dierickx, MD
A Novel Thermo-mechanical System Enhanced Transdermal Delivery of Hydr..Amnon C. Sintov, Maja A. Hofmann
Wound Healing Process After Thermomechanical Skin Ablation.Georgios Kokolakis, Leonie von Grawert, Martina Ulrich, Juergen Lademann, Torsten Zuberbier, and M
The Toxic Edge - A Novel Treatment for Refractory Erythema and Flushin..Or Friedman, MD, Amir Koren, MD, Roni Niv, MD, Joseph N. Mehrabi, BSc and Ofir Artzi, MD
The Scar Bane Without the Pain: A New Approach in the Treatment of Ele..Ofir Artzi, Amir Koren, Roni Niv, Joseph N. Mehrabi, Or Friedman
A new approach in the treatment of pediatric hypertrophic burn scars: ..Ofir Artzi MD, Amir Koren MD, Roni Niv MD, Joseph N. Mehrabi, Jacob Mashiah MD, Or Friedman MD
Enhanced percutaneous delivery of Beta-blockers using thermal resurfac..Jacob Mashiah, MD, Efrat Bar-Ilan, MD, Amir Koren, MD, Or Friedman, MD, Eyal Zur, RPh, Ofir Artzi, M
An Enhanced Transcutenous Delivery of Botulinum Toxin for the Treatmen..Bar Ilan E, Koren A. Shehadeh W., Mashiah J., Sprecher E., Artzi O.
Treatment of Port Wine Stain with Tixel Induced Rapamycin Delivery Fol..Ofir Artzi, Jos N. Mehrabi, Lee Heyman, Or Friedman, Jacob Mashiah.
The neck doesn't lie - Tixel® the safe and low-risk treatment option ..Dr. med. Arna Shab, Dr. med. Catharina Shab
Case Study: Treating Severe PhotoageingDr. Harryono Judodihardjo
Fractional Treatment of Aging Skin with Tixel, a Clinical and Histolog..Monica Elman, Nathalie Fournier, Gilbert Barnיon, Eric F. Bernstein and Gary Lask.
Fractional vaporization of tissue with an oscillatory array of high te..GARY LASK MD, MONICA ELMAN MD , NATHALIE FOURNIER, MD & MICHAEL SLATKINE, PhD