Tixel is powered by TMA (Thermo-Mechanical Ablation), a non-laser fractional treatment technology that can transfer thermal energy to the skin very quickly and safely. The energy is emitted through a matrix of tiny pyramid-shaped pins made of biocompatible materials covering a treatment area of 1cm². The pins are heated to a temperature of 400°C, similar to the temperature generated by a CO₂ laser beam when it interacts with the skin.

During treatment, the pins are introduced at a precisely controlled speed to the surface of the skin, after which the thermal energy stored in the pins is rapidly transferred to the skin upon brief contact lasting only a few milliseconds. The ensuant evaporation of water from the skin occurs instantaneously, resulting in the formation of tiny micropores in the treatment zone. The tiny pyramids hold a limited amount of energy and evaporate the upper layers of the skin in a controlled manner without causing burns or charring in the tissue, a side effect often seen with other energy sources such as laser.

Tissue evaporation by the tip upon brief contact with the skin


Unlike the typical micropores seen in fractional CO₂ laser treatments, Tixel micropores are free from necrotic tissue. The narrower zones of epidermal and dermal coagulation with Tixel contribute to rapid healing and treatment safety without sacrificing efficacy.

Laser vs Tixel


Epidermal necrotic zone measuring 330µm diameter, papillary dermal coagulation zone measuring 170µm depth.


Epidermal coagulation zone measuring 160µm diameter, papillary dermal coagulation zone measuring 170µm of depth.


Tixel can perform either ablative or non-ablative treatments. The extent of thermal damage generated is closely related to the choice of the tip and to pulse duration. By adjusting treatment parameters, the physician can control the extent of ablation, the thermal effect, downtime and duration of healing.

Ablative Non Ablative
Pulse duration
Vaporised tissues Epidermis & upper papillary dermis None None
Thermal effect Papillary dermis Papillary dermis Epidermis
Healing time (days) 3 2 1
Downtime (days) 1 1 0
Skin permeability No No Yes


The permeability of porcine skin treated by Tixel to Verapamil Hydrochloride, a hydrophilic drug molecule, MW 495 Da, is presented below.
Tixel is useful for pretreating skin in combination with cosmeceuticals.

Download Scientific Paper

The Novoxel devices’ intended use does not currently include tissue permeability enhancement



Laser vs Tixel, periorbital treatment.

Day 2 after first session. Photos courtesy of Monica Elman M.D.

Side by side comparison of fractional laser vs.
Tixel, 3 passes of each on the forehead.

Photos courtesy of Monica Elman M.D.

Facial treatment


Before and after